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Literature summary for 2.4.2.2 extracted from

  • Tang, Y.; Ni, M.; Wu, W.; Sun, J.; Zhou, C.
    Biotransformation of the antitumor intermediate 5-fluorouridine by recombinant Escherichia coli with high pyrimidine nucleoside phosphorylase activity (2010), Biocatal. Biotransform., 28, 130-136.
No PubMed abstract available

Application

Application Comment Organism
synthesis overexpression of enzyme in Escherichia coli, medium optimization and presence of uridine and 5-fluorouracil results in conversion of more than 90% of uridine to 5-fluorouridine by the cells Klebsiella aerogenes

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Klebsiella aerogenes

Organism

Organism UniProt Comment Textmining
Klebsiella aerogenes
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Klebsiella aerogenes CMCC 45103
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