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Literature summary for 2.4.2.31 extracted from

  • Shimoyama, M.; Tsuchiya, M.; Hara, N.; Yamada, K.; Osago, H.
    Molecular cloning and characterization of arginine-specific ADP-ribosyltransferases from chicken bone marrow cells (1997), Adv. Exp. Med. Biol., 419, 137-144.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
2-mercaptoethanol required by AT1 transferase, activates AT2 transferase Gallus gallus

Cloned(Commentary)

Cloned (Comment) Organism
in COS 7 cells transiently transfected with AT1 cDNA activity is detected in the culture medium. In COS 7 cells transfected with AT2 CDNA activity is found in both culture medium and cell lysate Gallus gallus

Inhibitors

Inhibitors Comment Organism Structure
NaCl inhibits AT1 transferase Gallus gallus

Metals/Ions

Metals/Ions Comment Organism Structure
NaCl activates AT2 transferase Gallus gallus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
32000
-
x * 32000, AT1 transferase, SDS-PAGE Gallus gallus
34000
-
x * 34000, AT2 transferase, SDS-PAGE Gallus gallus
35318
-
x * 35318, AT1 transferase, calculation from nucleotide sequence Gallus gallus

Organism

Organism UniProt Comment Textmining
Gallus gallus
-
2 enzyme forms: AT1 and AT2
-

Source Tissue

Source Tissue Comment Organism Textmining
bone marrow
-
Gallus gallus
-
erythrocyte very low activity Gallus gallus
-
heart low activity Gallus gallus
-
leukocyte high activity Gallus gallus
-
liver
-
Gallus gallus
-
lung
-
Gallus gallus
-
skeletal muscle low activity Gallus gallus
-
spleen
-
Gallus gallus
-

Subunits

Subunits Comment Organism
? x * 35318, AT1 transferase, calculation from nucleotide sequence Gallus gallus
? x * 34000, AT2 transferase, SDS-PAGE Gallus gallus
? x * 32000, AT1 transferase, SDS-PAGE Gallus gallus