Organism | UniProt | Comment | Textmining |
---|---|---|---|
Clostridioides difficile | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
actin + NAD+ | - |
Clostridioides difficile | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
binary toxin | - |
Clostridioides difficile |
CDT | - |
Clostridioides difficile |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.5 | - |
assay at | Clostridioides difficile |
General Information | Comment | Organism |
---|---|---|
physiological function | enzyme is an actin-specific ADP-ribosyltransferase, called binary toxin CDT, present in about 6% of strains isolated from patients with suspected Peptoclostridium difficile-associated diarrhea or colitis. All binary toxin-positive strains tested also produce toxins TcdB and/or TcdA. However, they have significant changes in the tcdA and tcdB genes and belong to variant toxinotypes III, IV, V, VII, IX, and XIII | Clostridioides difficile |