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Literature summary for 2.4.2.4 extracted from

  • Ogiuchi, Y.; Maruoka, Y.; Ando, T.; Kobayashi, M.; Ogiuchi, H.
    Thymidylate synthase, thymidine phosphorylase and orotate phosphoribosyl transferase levels as predictive factors of chemotherapy in oral squamous cell carcinoma (2008), Acta Histochem. Cytochem., 41, 39-46.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
additional information thymidine phosphorylase demonstrates differential expression depending on age, there is no remarkable difference in the mRNA and protein expression of thymidine phosphorylase due to the response in chemotherapy with TS-1 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
oral squamous cell carcinoma cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5'-deoxy-5-fluorouridine + phosphate
-
Homo sapiens 5-fluorouracil + 5-deoxy-D-ribose 1-phosphate
-
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