Literature summary for 2.4.2.4 extracted from

Stoebner, P.E.; Le Gallic, L.; Berthe, M.L.; Boulle, N.; Lallemant, B.; Marque, M.; Gaspard, C.; Delfour, C.; Lavabre-Bertrand, T.; Martinez, J.; Meunier, L.
Decreased expression of thymidine phosphorylase/platelet-derived endothelial cell growth factor in basal cell carcinomas (2008), Exp. Dermatol., 17, 908-915.

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Application

Application	Comment	Organism
medicine	thymidine phosphorylase is associated with tumor angiogenesis	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
basal cell carcinoma cell	thymidine phosphorylase mRNA levels are low and statistically not different in whole basal cell carcinoma cells and normal skin and are strongly downregulated in laser capture microdissected-basal cell carcinoma cells as compared with laser capture microdissected-normal epidermis	Homo sapiens	-
epidermis	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
thymidine + phosphate	-	Homo sapiens	thymine + 2-deoxy-D-ribose 1-phosphate	-	?

Synonyms

Synonyms	Comment	Organism
PD-ECGF	-	Homo sapiens
platelet-derived endothelial cell growth factor	-	Homo sapiens

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Release 2023.1 (January 2023)