BRENDA - Enzyme Database
show all sequences of 2.4.2.48

Crystal structure of archaeosine tRNA-guanine transglycosylase

Ishitani, R.; Nureki, O.; Fukai, S.; Kijimoto, T.; Nameki, N.; Watanabe, M.; Kondo, H.; Sekine, M.; Okada, N.; Nishimura, S.; Yokoyama, S.; J. Mol. Biol. 318, 665-677 (2002) View publication on PubMed

Data extracted from this reference:

Crystallization (Commentary)
Crystallization (Commentary)
Organism
crystal structures of the enzyme at 2.2 A resolution and its complexes with guanine and 7-cyano-7-deazaguanine, at 2.3 and 2.5 A resolutions, respectively
Pyrococcus horikoshii
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Zn2+
contains a zinc-binding site
Pyrococcus horikoshii
Molecular Weight [Da]
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
66000
-
-
Pyrococcus horikoshii
Organism
Organism
UniProt
Commentary
Textmining
Pyrococcus horikoshii
O58843
-
-
Subunits
Subunits
Commentary
Organism
homodimer
-
Pyrococcus horikoshii
Synonyms
Synonyms
Commentary
Organism
archaeosine tRNA-guanine transglycosylase
-
Pyrococcus horikoshii
ArcTGT
-
Pyrococcus horikoshii
Crystallization (Commentary) (protein specific)
Crystallization
Organism
crystal structures of the enzyme at 2.2 A resolution and its complexes with guanine and 7-cyano-7-deazaguanine, at 2.3 and 2.5 A resolutions, respectively
Pyrococcus horikoshii
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Zn2+
contains a zinc-binding site
Pyrococcus horikoshii
Molecular Weight [Da] (protein specific)
Molecular Weight [Da]
Molecular Weight Maximum [Da]
Commentary
Organism
66000
-
-
Pyrococcus horikoshii
Subunits (protein specific)
Subunits
Commentary
Organism
homodimer
-
Pyrococcus horikoshii
Other publictions for EC 2.4.2.48
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
738326
Nomura
Correlation between the stabil ...
Methanosarcina acetivorans
Genes Cells
21
41-52
2016
-
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-
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1
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1
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1
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739201
Kawamura
Multisite-specific archaeosine ...
Thermoplasma acidophilum, Thermoplasma acidophilum HO-62
Nucleic Acids Res.
44
1894-1908
2016
-
-
1
-
-
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-
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2
-
12
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1
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745926
Kawamura
Multisite-specific archaeosin ...
Pyrococcus horikoshii, Thermoplasma acidophilum, Pyrococcus horikoshii OT-3
Nucleic Acids Res.
44
1894-1908
2015
-
-
2
-
-
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10
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1
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4
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4
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4
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728740
Nomura
Purification and comparison of ...
Methanosarcina acetivorans, Methanosarcina acetivorans DSM 2834
Protein Expr. Purif.
88
13-19
2013
-
-
1
-
-
-
-
2
-
1
3
2
-
4
-
-
1
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2
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2
1
2
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2
1
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1
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1
3
2
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1
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2
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2
1
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2
1
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2
2
680738
Sabina
The RNA-binding PUA domain of ...
Pyrococcus furiosus
J. Biol. Chem.
281
6993-7001
2006
-
-
1
-
1
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1
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-
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1
-
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1
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1
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722005
Ishitani
Alternative tertiary structure ...
Pyrococcus horikoshii
Cell
113
383-394
2005
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1
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1
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1
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-
722944
Ishitani
Crystal structure of archaeosi ...
Pyrococcus horikoshii
J. Mol. Biol.
318
665-677
2002
-
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1
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1
1
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1
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1
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719802
Bai
Hypermodification of tRNA in t ...
Methanocaldococcus jannaschii
J. Biol. Chem.
275
28731-28738
2000
-
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1
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1
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1
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1
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1
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3
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2
2
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1
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1
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3
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2
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2
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3
3
-
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722604
Watanabe
Biosynthesis of archaeosine, a ...
Haloferax volcanii, Haloferax volcanii ATCC 29605
J. Biol. Chem.
272
20146-20151
1997
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2
1
2
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2
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1
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4
1
1
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1
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1
2
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1
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4
1
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1
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