Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.4.2.59 extracted from

  • Zhang, X.; Eser, B.; Chanani, P.; Begley, T.; Ealick, S.
    Structural basis for iron-mediated sulfur transfer in archael and yeast thiazole synthases (2016), Biochemistry, 55, 1826-1838 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.4.2.59

Crystallization (Commentary)

Crystallization (Comment) Organism
enzyme complexed with ADP-ribulose, hanging drop vapor diffusion method, using 1.05 M potassium/sodium tartrate, 0.1 M CHES/sodium hydroxide, pH 9.5 and 0.2 M lithium sulfate Methanocaldococcus jannaschii
enzyme complexes with glycine imine intermediate and iron, hanging drop vapor diffusion method, using 1.0 M sodium citrate, 0.1 M CHES/sodium hydroxide, pH 9.5 Methanotorris igneus

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ dependent on Methanocaldococcus jannaschii
Fe2+ dependent on Methanotorris igneus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NAD+ + glycine + sulfide Methanocaldococcus jannaschii
-
 nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + 3 H2O
-
 ?
NAD+ + glycine + sulfide Methanotorris igneus
-
 nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + 3 H2O
-
 ?
NAD+ + glycine + sulfide Methanocaldococcus jannaschii DSM 2661
-
 nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + 3 H2O
-
 ?
NAD+ + glycine + sulfide Methanocaldococcus jannaschii ATCC 43067
-
 nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + 3 H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Methanocaldococcus jannaschii Q58018
-
-
Methanocaldococcus jannaschii ATCC 43067 Q58018
-
-
Methanotorris igneus F6BCS4
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NAD+ + glycine + sulfide
-
 Methanocaldococcus jannaschii nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + 3 H2O
-
 ?
NAD+ + glycine + sulfide
-
 Methanotorris igneus nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + 3 H2O
-
 ?
NAD+ + glycine + sulfide
-
 Methanocaldococcus jannaschii DSM 2661 nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + 3 H2O
-
 ?
NAD+ + glycine + sulfide
-
 Methanocaldococcus jannaschii ATCC 43067 nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate + 3 H2O
-
 ?

Synonyms

Synonyms Comment Organism
MJ0601
-
 Methanocaldococcus jannaschii
Thi4
-
 Methanocaldococcus jannaschii
Thi4
-
 Methanotorris igneus