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Literature summary for 2.4.2.8 extracted from

  • Arnold, W.J.; Kelley, W.N.
    Human hypoxanthine-guanine phosphoribosyltransferase. Purification and subunit structure (1971), J. Biol. Chem., 246, 7398-7404.
    View publication on PubMed

General Stability

General Stability Organism
glycerol or sucrose or dimethylsulfoxide stabilizes the purified enzyme at -70°C Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
68000
-
gel filtration Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
no glycoprotein no carbohydrate Homo sapiens

Purification (Commentary)

Purification (Comment) Organism
3 isoenzymes Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
guanine + 5-phospho-alpha-D-ribose 1-diphosphate
-
Homo sapiens GMP + diphosphate
-
?
hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate
-
Homo sapiens IMP + diphosphate
-
?

Subunits

Subunits Comment Organism
dimer 2 * 34000-34700, SDS-PAGE Homo sapiens