Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli strain C41 | Mycobacterium tuberculosis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.058 | - |
dimethylallyl diphosphate | in 50 mM sodium phosphate (pH 7.0), at 37°C | Mycobacterium tuberculosis | |
0.163 | - |
isopentenyl diphosphate | in 50 mM sodium phosphate (pH 7.0), at 37°C | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Mycobacterium tuberculosis CDC 1551 | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni-NTA column chromatography | Mycobacterium tuberculosis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dimethylallyl diphosphate + isopentenyl diphosphate | - |
Mycobacterium tuberculosis | (E)-geranyl diphosphate + diphosphate | - |
? | |
dimethylallyl diphosphate + isopentenyl diphosphate | - |
Mycobacterium tuberculosis CDC 1551 | (E)-geranyl diphosphate + diphosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
(E)-geranyl diphosphate synthase | - |
Mycobacterium tuberculosis |
Rv0989c | - |
Mycobacterium tuberculosis |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.012 | - |
isopentenyl diphosphate | in 50 mM sodium phosphate (pH 7.0), at 37°C | Mycobacterium tuberculosis | |
0.085 | - |
dimethylallyl diphosphate | in 50 mM sodium phosphate (pH 7.0), at 37°C | Mycobacterium tuberculosis |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is able to provide the geranyl diphosphate precursor required for efficient production of both double bond isomers of farnesyl diphosphate in Mycobacterium tuberculosis | Mycobacterium tuberculosis |