Literature summary for 2.5.1.22 extracted from

Pegg, A.E.
Inhibition of aminopropyltransferases (1983), Methods Enzymol., 94, 294-297.

Inhibitors

Inhibitors	Comment	Organism
1,3-diaminopropane	-	Rattus norvegicus
1,8-diaminooctane	-	Rattus norvegicus
1,9-diamino-4-azanonane	weak	Rattus norvegicus
1,9-Diamino-5-azanonane	weak	Rattus norvegicus
3,3'-Diaminodipropylamine	weak	Rattus norvegicus
5'-ethylthioadenosine	-	Rattus norvegicus
5'-methylthioadenosine	strong	Bos taurus
5'-methylthioadenosine	strong	Rattus norvegicus
5'-methylthiotubercidin	strong, in vivo and in vitro, kinetics	Rattus norvegicus
5-[5'-deoxy-5'-(C)-4',5'-didehydroadenosyl]-L-ornithine	i.e. compound A9154C, prostate	Rattus norvegicus
additional information	-	Bos taurus
additional information	not inhibitory: cyclohexylamine or dicyclohexylamine; overview on inhibitors	Rattus norvegicus
putrescine	-	Bos taurus
putrescine	-	Rattus norvegicus
S-5'-Deoxyadenosyl-(5')-1-methyl-3-(methylthio)propylamine	-	Rattus norvegicus
S-Adenosyl-1,8-diamino-3-thiooctane	weak, prostate	Rattus norvegicus
S-Adenosyl-4-methylthiobutyrate	prostate	Rattus norvegicus
S-Adenosyl-4-thiobutyrate methylester	prostate	Rattus norvegicus
S-adenosyl-D-methionine	-	Rattus norvegicus
S-adenosyl-L-methionine	prostate	Rattus norvegicus

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-
Rattus norvegicus	-	-	-

Source Tissue	Comment	Organism	Textmining
brain	-	Rattus norvegicus	-
brain	-	Bos taurus	-
prostate gland	-	Rattus norvegicus	-

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Release 2023.1 (January 2023)