Literature summary for 2.5.1.55 extracted from

Coutrot, P.; Dumarcay, S.; Finance, C.; Tabyaoui, M.; Grison, C.
Investigation of new potent KDO-8-phosphate synthetase inhibitors (1999), Bioorg. Med. Chem. Lett., 9, 949-952.

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Inhibitors

Inhibitors	Comment	Organism	Structure
(Z,E)-D-Glucophosphoenolpyruvate	and its carboxylic ester derivatives	Gram-negative bacteria

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
phosphoenolpyruvate + D-arabinose-5-phosphate + H2O	Gram-negative bacteria	second step in the biosynthesis of 3-deoxy-D-manno-2-octulosonic acid	2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Gram-negative bacteria	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
phosphoenolpyruvate + D-arabinose 5-phosphate	-	Gram-negative bacteria	2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate	-	?
phosphoenolpyruvate + D-arabinose-5-phosphate + H2O	second step in the biosynthesis of 3-deoxy-D-manno-2-octulosonic acid	Gram-negative bacteria	2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate	-	?

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Release 2023.1 (January 2023)