Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Nonidet P-40 | - |
Saccharomyces cerevisiae | |
Nonidet P-40 | the plant enzyme activity is enhanced by detergent | Nicotiana tabacum | |
Nonidet P-40 | the plant enzyme activity is enhanced by detergent | Solanum lycopersicum |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | plant enzyme is inhibited by mutant Rab lacking a prenylation consence sequence | Nicotiana tabacum | |
additional information | plant enzyme is inhibited by mutant Rab lacking a prenylation consence sequence | Solanum lycopersicum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
geranylgeranyl diphosphate + protein-cysteine | Saccharomyces cerevisiae | - |
S-geranylgeranyl-protein + diphosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Nicotiana tabacum | - |
- |
- |
Saccharomyces cerevisiae | - |
- |
- |
Solanum lycopersicum | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
geranylgeranyl diphosphate + protein-cysteine | - |
Saccharomyces cerevisiae | S-geranylgeranyl-protein + diphosphate | - |
? | |
geranylgeranyl diphosphate + protein-cysteine | enzyme attaches geranylgeranyl groups to two C-terminal cysteines in Ras-related GTPases of a single family, the Rab family, Ypt/Sec4 in lower eukaryotes, that terminate in XXCC, XCXC and CCXX motifs, reaction only if Rab is bound to a carrier protein termed Rab escort protein, REP | Saccharomyces cerevisiae | S-geranylgeranyl-protein + diphosphate | - |
? | |
geranylgeranyl diphosphate + protein-cysteine | substrate are three tomato cDNAs endcoding Rab-like proteins: LeRab1A, B and C with mutant and wild-type prenylation motif, LeRab1B is the best substrate for the plant enzyme, but LeRab1A is the best substrate for yeast enzyme | Saccharomyces cerevisiae | S-geranylgeranyl-protein + diphosphate | - |
? | |
geranylgeranyl diphosphate + protein-cysteine | substrate are three tomato cDNAs endcoding Rab-like proteins: LeRab1A, B and C with mutant and wild-type prenylation motif, LeRab1B is the best substrate for the plant enzyme, but LeRab1A is the best substrate for yeast enzyme | Nicotiana tabacum | S-geranylgeranyl-protein + diphosphate | - |
? | |
geranylgeranyl diphosphate + protein-cysteine | substrate are three tomato cDNAs endcoding Rab-like proteins: LeRab1A, B and C with mutant and wild-type prenylation motif, LeRab1B is the best substrate for the plant enzyme, but LeRab1A is the best substrate for yeast enzyme | Solanum lycopersicum | S-geranylgeranyl-protein + diphosphate | - |
? |