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Literature summary for 2.5.1.61 extracted from

  • Araujo, L.S.; Lombardo, M.E.; Batlle, A.M.D.C.
    Inhibition of porphobilinogenase by porphyrins in Saccharomyces cerevisiae (1994), Int. J. Biochem., 26, 1377-1381.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.012
-
porphobilinogen wild type D273-10B Saccharomyces cerevisiae
0.0195
-
porphobilinogen mutant B231 Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
porphobilinogen Saccharomyces cerevisiae
-
?
-
?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
wild-type D273-10B, mutant B231
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
porphobilinogenase system Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4 porphobilinogen in the presence of uroporphyrinogen III cosynthase, EC 4.2.1.75 Saccharomyces cerevisiae uroporphyrinogen III + 4 NH3
-
?
4 porphobilinogen + H2O
-
Saccharomyces cerevisiae hydroxylmethylbilane + 4 NH3
-
?
porphobilinogen
-
Saccharomyces cerevisiae ?
-
?

Synonyms

Synonyms Comment Organism
PBG-D
-
Saccharomyces cerevisiae
PBG-deaminase
-
Saccharomyces cerevisiae