Protein Variants | Comment | Organism |
---|---|---|
additional information | ceaS1 mutants with reduced clavulanic acid production compared with wild-type strain, ceaS1/ceaS2 double mutants and ceaS2 frameshift mutants with completely blocked clavulanic acid biosynthesis | Streptomyces clavuligerus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
59078 | - |
x * 59078, CeaS1, sequence calculation | Streptomyces clavuligerus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glyceraldehyde 3-phosphate + L-arginine | Streptomyces clavuligerus | catalyzes the first reaction of the clavulanic acid biosynthesis pathway | N2-(2-carboxyethyl)-L-arginine + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces clavuligerus | Q6TA05 | wild-type strain NRRL3585, two paralogous genes ceaS1 and ceaS2 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glyceraldehyde 3-phosphate + L-arginine | - |
Streptomyces clavuligerus | N2-(2-carboxyethyl)-L-arginine + phosphate | - |
? | |
D-glyceraldehyde 3-phosphate + L-arginine | catalyzes the first reaction of the clavulanic acid biosynthesis pathway | Streptomyces clavuligerus | N2-(2-carboxyethyl)-L-arginine + phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 59078, CeaS1, sequence calculation | Streptomyces clavuligerus |
Synonyms | Comment | Organism |
---|---|---|
carboxyethylarginine synthase | - |
Streptomyces clavuligerus |
CEAS | - |
Streptomyces clavuligerus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
thiamine diphosphate | thiamine diphosphate-dependent | Streptomyces clavuligerus |