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Literature summary for 2.6.1.18 extracted from

  • Wilding, M.; Peat, T.S.; Newman, J.; Scott, C.
    A beta-alanine batabolism pathway containing a highly promiscuous omega-transaminase in the 12-aminododecanate-degrading Pseudomonas sp. strain AAC (2016), Appl. Environ. Microbiol., 82, 3846-3856.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.6.1.18

Crystallization (Commentary)

Crystallization (Comment) Organism
protein forms a dimer containing a large activesite pocket and unusual phosphorylated histidine residues Pseudomonas sp.

Protein Variants

Protein Variants Comment Organism
R414K 19.9% of wild-type activity with substrate beta-alanine, 9.6% with substrate cadaverine, 20.5% with substrate 1,3-diaminopropane Pseudomonas sp.

Organism

Organism UniProt Comment Textmining
Pseudomonas sp.
-
-
-
Pseudomonas sp. AAC
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,10-decanediamine + propionaldehyde 97.2% of the activity with amine donor 8-aminooctanoate Pseudomonas sp. 10-aminodecanaldehyde + 1-aminopropane
-
 ?
1,10-decanediamine + propionaldehyde 97.2% of the activity with amine donor 8-aminooctanoate Pseudomonas sp. AAC 10-aminodecanaldehyde + 1-aminopropane
-
 ?
1,6-hexamethylenediamine + propionaldehyde 55.5% of the activity with amine donor 8-aminooctanoate Pseudomonas sp. ? + 1-aminopropane
-
 ?
1,6-hexamethylenediamine + propionaldehyde 55.5% of the activity with amine donor 8-aminooctanoate Pseudomonas sp. AAC ? + 1-aminopropane
-
 ?
12-aminododecanoate + propionaldehyde
-
 Pseudomonas sp. 12-oxododecanoate + 1-aminopropane
-
 ?
12-aminododecanoate + propionaldehyde
-
 Pseudomonas sp. AAC 12-oxododecanoate + 1-aminopropane
-
 ?
4-aminobutanoate + butanaldehyde 4-aminobutanoate, 91% of the activity with amine donor 8-aminooctanoate Pseudomonas sp. 4-oxobutanoate + 1-aminobutane
-
 ?
4-aminobutanoate + butanaldehyde 4-aminobutanoate, 91% of the activity with amine donor 8-aminooctanoate Pseudomonas sp. AAC 4-oxobutanoate + 1-aminobutane
-
 ?
5-aminopentanoate + glyceraldehyde 5-aminopentanoate, 52.7% of the activity with amine donor 8-aminooctanoate, glyceraldehyde , 34.1% of the activity with amine acceptor butanaldehyde Pseudomonas sp. 5-oxopentanoate + 1-amino-2,3-dihydroxypropane
-
 ?
6-aminohexanoate + glyceraldehyde 62.5% of the activity with amine donor 8-aminooctanoate Pseudomonas sp. 6-oxohexanoate + 1-amino-2,3-dihydroxypropane
-
 ?
6-aminohexanol + propionaldehyde 70% of the activity with amine donor 8-aminooctanoate Pseudomonas sp. 6-oxohexanol + 1-aminopropane
-
 ?
7-aminoheptanoate + glyceraldehyde 68.9% of the activity with amine donor 8-aminooctanoate Pseudomonas sp. 7-oxoheptanoate + 1-amino-2,3-dihydroxypropane
-
 ?
8-aminooctanoate + glyceraldehyde
-
 Pseudomonas sp. 8-oxooctanoate + 1-amino-2,3-dihydroxypropane
-
 ?
beta-alanine + propionaldehyde beta-alanine, 54% of the activity with amine donor 8-aminooctanoate, propionaldehyde, 68.3% of the activity with amine acceptor butanaldehyde Pseudomonas sp. malonic semialdehyde + 1-aminopropane
-
 ?
cadaverine + propionaldehyde 86.2% of the activity with amine donor 8-aminooctanoate Pseudomonas sp. ? + 1-aminopropane
-
 ?
DL-aminoisobutanoate + propionaldehyde 62.2% of the activity with amine donor 8-aminooctanoate Pseudomonas sp. oxoisobutanoate + 1-aminopropane
-
 ?
additional information enzyme is active with a broad substrate range which includes alpha-, beta- and omega-amino acids, as well as alpha,omega-diamines and a number of other industrially relevant compounds Pseudomonas sp. ?
-
 ?
additional information enzyme is active with a broad substrate range which includes alpha-, beta- and omega-amino acids, as well as alpha,omega-diamines and a number of other industrially relevant compounds Pseudomonas sp. AAC ?
-
 ?

Synonyms

Synonyms Comment Organism
FG99_15380
-
 Pseudomonas sp.