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Literature summary for 2.6.1.29 extracted from
- Lysine catabolism in Streptomyces spp. is primarily through cadaverine: beta-lactam producers also make alpha-aminoadipate (1989), J. Bacteriol., 171, 299-302.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cadaverine + 2-oxoglutarate | Streptomyces griseus | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? |  |
| cadaverine + 2-oxoglutarate | Streptomyces phaeochromogenes | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces venezuelae | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces glaucescens | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces rimosus | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces lividans | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Amycolatopsis lactamdurans | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces viridochromogenes | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces parvulus | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces clavuligerus | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces glaucescens GLAO | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces viridochromogenes CUB416 | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces phaeochromogenes B2196 | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces parvulus ISP5048 | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces lividans TK24 | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces clavuligerus NRRL 3585 | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces griseus NRRL 3851 | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces venezuelae ISP5230 | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Amycolatopsis lactamdurans NRRL 3802 | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | Streptomyces rimosus NRRL 2234 | enzyme catalyzes the second step in lysine catabolism | 5-aminopentanal + L-glutamate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Amycolatopsis lactamdurans | - |
- |
- |
| Amycolatopsis lactamdurans NRRL 3802 | - |
- |
- |
| Streptomyces clavuligerus | - |
- |
- |
| Streptomyces clavuligerus NRRL 3585 | - |
- |
- |
| Streptomyces glaucescens | - |
- |
- |
| Streptomyces glaucescens GLAO | - |
- |
- |
| Streptomyces griseus | - |
- |
- |
| Streptomyces griseus NRRL 3851 | - |
- |
- |
| Streptomyces lividans | - |
- |
- |
| Streptomyces lividans TK24 | - |
- |
- |
| Streptomyces parvulus | - |
- |
- |
| Streptomyces parvulus ISP5048 | - |
- |
- |
| Streptomyces phaeochromogenes | - |
- |
- |
| Streptomyces phaeochromogenes B2196 | - |
- |
- |
| Streptomyces rimosus | - |
- |
- |
| Streptomyces rimosus NRRL 2234 | - |
- |
- |
| Streptomyces venezuelae | - |
- |
- |
| Streptomyces venezuelae ISP5230 | - |
- |
- |
| Streptomyces viridochromogenes | - |
- |
- |
| Streptomyces viridochromogenes CUB416 | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.00064 | - |
- |
Amycolatopsis lactamdurans |
| 0.00064 | - |
- |
Streptomyces parvulus |
| 0.0011 | - |
- |
Streptomyces rimosus |
| 0.00116 | - |
- |
Streptomyces glaucescens |
| 0.00156 | - |
- |
Streptomyces venezuelae |
| 0.00167 | - |
- |
Streptomyces viridochromogenes |
| 0.00192 | - |
- |
Streptomyces griseus |
| 0.0021 | - |
- |
Streptomyces lividans |
| 0.00238 | - |
- |
Streptomyces clavuligerus |
| 0.00248 | - |
- |
Streptomyces phaeochromogenes |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cadaverine + 2-oxoglutarate | - |
Streptomyces griseus | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces phaeochromogenes | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces venezuelae | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces glaucescens | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces rimosus | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces lividans | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Amycolatopsis lactamdurans | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces viridochromogenes | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces parvulus | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces clavuligerus | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces griseus | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces phaeochromogenes | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces venezuelae | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces glaucescens | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces rimosus | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces lividans | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Amycolatopsis lactamdurans | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces viridochromogenes | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces parvulus | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces clavuligerus | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces glaucescens GLAO | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces glaucescens GLAO | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces viridochromogenes CUB416 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces viridochromogenes CUB416 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces phaeochromogenes B2196 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces phaeochromogenes B2196 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces parvulus ISP5048 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces parvulus ISP5048 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces lividans TK24 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces lividans TK24 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces clavuligerus NRRL 3585 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces clavuligerus NRRL 3585 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces griseus NRRL 3851 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces griseus NRRL 3851 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces venezuelae ISP5230 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces venezuelae ISP5230 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Amycolatopsis lactamdurans NRRL 3802 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Amycolatopsis lactamdurans NRRL 3802 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | - |
Streptomyces rimosus NRRL 2234 | 5-aminopentanal + L-glutamate | - |
? | |
| cadaverine + 2-oxoglutarate | enzyme catalyzes the second step in lysine catabolism | Streptomyces rimosus NRRL 2234 | 5-aminopentanal + L-glutamate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Streptomyces griseus |
| 37 | - |
assay at | Streptomyces phaeochromogenes |
| 37 | - |
assay at | Streptomyces venezuelae |
| 37 | - |
assay at | Streptomyces glaucescens |
| 37 | - |
assay at | Streptomyces rimosus |
| 37 | - |
assay at | Streptomyces lividans |
| 37 | - |
assay at | Amycolatopsis lactamdurans |
| 37 | - |
assay at | Streptomyces viridochromogenes |
| 37 | - |
assay at | Streptomyces parvulus |
| 37 | - |
assay at | Streptomyces clavuligerus |
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