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Literature summary for 2.6.1.39 extracted from
- Separation and specificity of the yeast glutamate-alpha-ketoadipate transaminase (1969), J. Biol. Chem., 244, 3352-3358.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | glutamate-alpha-ketoadipate transaminase II | Saccharomyces cerevisiae | 5737 | - |
| mitochondrion | glutamate-alpha-ketoadipate transaminase I | Saccharomyces cerevisiae | 5739 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 100000 | - |
mitochondrial isoform glutamate-alpha-ketoadipate transaminase I, gel filtration | Saccharomyces cerevisiae |
| 140000 | - |
cytoplasmic isoform glutamate-alpha-ketoadipate transaminase II, gel filtration | Saccharomyces cerevisiae |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-2-aminoadipate + 2-oxoglutarate | Saccharomyces cerevisiae | - |
2-oxoadipate + L-glutamate | - |
r |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
bakers' yeast, haploid strains MO-11-48A and X1049-2B, diploid strain F2, clonal isolate of commercial bakers' yeast | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Saccharomyces cerevisiae |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-2-aminoadipate + 2-oxoglutarate | - |
Saccharomyces cerevisiae | 2-oxoadipate + L-glutamate | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GKAT | - |
Saccharomyces cerevisiae |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 45 | 70 | stable against heating at 45°C, 50°C, 55°C, 60°C, 65°C and 70°C for 10 min | Saccharomyces cerevisiae |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.5 | - |
- |
Saccharomyces cerevisiae |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Saccharomyces cerevisiae | |
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Release 2023.1 (January 2023)
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