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Literature summary for 2.7.1.191 extracted from

  • Stock, J.; Waygood, E.; Meadow, N.; Postma, P.; Roseman, S.
    Sugar transport by the bacterial phosphotransferase system. The glucose receptors of the Salmonella typhimurium phosphotransferase system (1982), J. Biol. Chem., 257, 14543-14552.
    View publication on PubMed
Search for more literature for 2.7.1.191

Inhibitors

Inhibitors Comment Organism Structure
additional information not inhibited by D-fructose Salmonella enterica

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.015
-
 D-glucose[side 1] at pH 7.5 and 25°C Salmonella enterica
0.02
-
 D-fructose[side 1] at pH 7.5 and 25°C Salmonella enterica
0.045
-
 D-mannose[side 1] at pH 7.5 and 25°C Salmonella enterica
0.2
-
 2-deoxy-D-glucose[side 1] at pH 7.5 and 25°C Salmonella enterica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
[protein]-Npi-phospho-L-histidine + 2-deoxy-D-glucose[side 1] Salmonella enterica
-
 [protein]-L-histidine + 2-deoxy-D-glucose 6-phosphate[side 2]
-
 ?
[protein]-Npi-phospho-L-histidine + D-fructose[side 1] Salmonella enterica
-
 [protein]-L-histidine + D-fructose 6-phosphate[side 2]
-
 ?
[protein]-Npi-phospho-L-histidine + D-glucose[side 1] Salmonella enterica
-
 [protein]-L-histidine + D-glucose 6-phosphate[side 2]
-
 ?
[protein]-Npi-phospho-L-histidine + D-mannose[side 1] Salmonella enterica
-
 [protein]-L-histidine + D-mannose 6-phosphate[side 2]
-
 ?

Organism

Organism UniProt Comment Textmining
Salmonella enterica
-
 serovar typhimurium
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[protein]-Npi-phospho-L-histidine + 2-deoxy-D-glucose[side 1]
-
 Salmonella enterica [protein]-L-histidine + 2-deoxy-D-glucose 6-phosphate[side 2]
-
 ?
[protein]-Npi-phospho-L-histidine + D-fructose[side 1]
-
 Salmonella enterica [protein]-L-histidine + D-fructose 6-phosphate[side 2]
-
 ?
[protein]-Npi-phospho-L-histidine + D-glucose[side 1]
-
 Salmonella enterica [protein]-L-histidine + D-glucose 6-phosphate[side 2]
-
 ?
[protein]-Npi-phospho-L-histidine + D-mannose[side 1]
-
 Salmonella enterica [protein]-L-histidine + D-mannose 6-phosphate[side 2]
-
 ?

Synonyms

Synonyms Comment Organism
enzyme IIMan
-
 Salmonella enterica
ptsM
-
 Salmonella enterica