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Literature summary for 2.7.1.21 extracted from

  • Tzeng, H.F.; Chang, Z.F.; Peng, S.E.; Wang, C.H.; Lin, J.Y.; Kou, G.H.; Lo, C.F.
    Chimeric polypeptide of thymidine kinase and thymidylate kinase of shrimp white spot syndrome virus: Thymidine kinase activity of the recombinant protein expressed in a baculovirus/insect cell system (2002), Virology, 299, 248-255.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Shrimp white spot syndrome virus

Inhibitors

Inhibitors Comment Organism Structure
TTP 83% inhibition at 1 mM, 43% inhibition at 0.1 mM, 15% inhibition at 0.01 mM Shrimp white spot syndrome virus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0041
-
thymidine pH 8, 25°C or 37°C Shrimp white spot syndrome virus
0.076
-
ATP pH 8, 25°C or 37°C Shrimp white spot syndrome virus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Shrimp white spot syndrome virus 5829
-

Organism

Organism UniProt Comment Textmining
Shrimp white spot syndrome virus
-
shrimp virus
-

Purification (Commentary)

Purification (Comment) Organism
-
Shrimp white spot syndrome virus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 2'-deoxyuridine
-
Shrimp white spot syndrome virus ADP + 2'-deoxyuridine 5'-phosphate
-
?
ATP + 5-bromo-2'-deoxyuridine
-
Shrimp white spot syndrome virus ADP + 5-bromo-2'-deoxyuridine 5'-phosphate
-
?
ATP + thymidine ATP can be substituted by GTP Shrimp white spot syndrome virus ADP + dTMP
-
?
ATP + thymidine ATP can be substituted by dGTP Shrimp white spot syndrome virus ADP + dTMP
-
?
ATP + thymidine ATP can be substituted by UTP Shrimp white spot syndrome virus ADP + dTMP
-
?
ATP + thymidine ATP can be substituted by dCTP Shrimp white spot syndrome virus ADP + dTMP
-
?
ATP + thymidine ATP can be substituted by dATP Shrimp white spot syndrome virus ADP + dTMP
-
?
ATP + thymidine ATP can be substituted by CTP Shrimp white spot syndrome virus ADP + dTMP
-
?