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Literature summary for 2.7.1.31 extracted from
- Studies on the purification and properties of D-glyceric acid kinase of liver (1957), J. Biol. Chem., 225, 949-958.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | - |
Bos taurus |  |
| EDTA | - |
Equus caballus | |
| EDTA | - |
Rattus norvegicus | |
| additional information | not: arsenite | Bos taurus | |
| additional information | not: arsenite | Equus caballus | |
| additional information | not: arsenite | Rattus norvegicus | |
| p-chloromercuribenzoate | not | Bos taurus | |
| p-chloromercuribenzoate | not | Equus caballus | |
| p-chloromercuribenzoate | not | Rattus norvegicus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Co2+ | no stimulatory effect | Rattus norvegicus | |
| Co2+ | no stimulatory effect | Bos taurus | |
| Co2+ | no stimulatory effect | Equus caballus | |
| Mg2+ | required | Rattus norvegicus | |
| Mg2+ | required | Bos taurus | |
| Mg2+ | required | Equus caballus | |
| Mg2+ | Km: 0.164 mM | Rattus norvegicus | |
| Mg2+ | Km: 0.164 mM | Bos taurus | |
| Mg2+ | Km: 0.164 mM | Equus caballus | |
| Mn2+ | no stimulatory effect | Rattus norvegicus | |
| Mn2+ | no stimulatory effect | Bos taurus | |
| Mn2+ | no stimulatory effect | Equus caballus | |
| additional information | no stimulatory effect by Zn2+ and Cu2+ | Rattus norvegicus | |
| additional information | no stimulatory effect by Zn2+ and Cu2+ | Bos taurus | |
| additional information | no stimulatory effect by Zn2+ and Cu2+ | Equus caballus | |
| Ni2+ | no stimulatory effect | Rattus norvegicus | |
| Ni2+ | no stimulatory effect | Bos taurus | |
| Ni2+ | no stimulatory effect | Equus caballus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Equus caballus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
- |
Bos taurus |
- |
Equus caballus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
| liver | - |
Bos taurus | - |
| liver | - |
Equus caballus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + (R)-glycerate | - |
Rattus norvegicus | ADP + 3-phospho-(R)-glycerate | - |
? | |
| ATP + (R)-glycerate | - |
Bos taurus | ADP + 3-phospho-(R)-glycerate | - |
? | |
| ATP + (R)-glycerate | - |
Equus caballus | ADP + 3-phospho-(R)-glycerate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Rattus norvegicus |
| 37 | - |
assay at | Bos taurus |
| 37 | - |
assay at | Equus caballus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | 7.7 | - |
Rattus norvegicus |
| 7.4 | 7.7 | - |
Bos taurus |
| 7.4 | 7.7 | - |
Equus caballus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5.2 | 8.2 | pH 5.2: about 30% of maximum activity, pH 8.2: about 90% of maximum activity | Rattus norvegicus |
| 5.2 | 8.2 | pH 5.2: about 30% of maximum activity, pH 8.2: about 90% of maximum activity | Bos taurus |
| 5.2 | 8.2 | pH 5.2: about 30% of maximum activity, pH 8.2: about 90% of maximum activity | Equus caballus |
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