Literature summary for 2.7.1.36 extracted from

Fu, Z.; Wang, M.; Potter, D.; Miziorko, H.M.; Kim, J.J.
The structure of a binary complex between a mammalian mevalonate kinase and ATP: insights into the reaction mechanism and human inherited disease (2002), J. Biol. Chem., 277, 18134-18142.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
crystals of mevalonate kinase-MgATP complex are grown at 4°C using the sitting drop method by mixing equal volumes of an enzyme solution containing 13 mg/ml protein, 1 mM ATP and 2 mM MgCl2 and a precipitant solution containing 100 mM HEPES buffer, pH 7.5 and 17.5% polyethylene glycol 5000 monomethylester, crystals appear after 3 days, crystal structure at 2.4 A resolution	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

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Release 2023.1 (January 2023)