Literature summary for 2.7.1.36 extracted from

Ikeda, S.; Nakamura, K.; Kogure, K.; Omori, Y.; Yamashita, S.; Kubota, K.; Mizutani, T.; Miyamoto, K.; Minegishi, T.
Effect of estrogen on the expression of luteinizing hormone-human chorionic gonadotropin receptor messenger ribonucleic acid in cultured rat granulosa cells (2008), Endocrinology, 149, 1524-1533.

Search for more literature for 2.7.1.36

Application

Application	Comment	Organism
medicine	luteinizing hormone receptor mRNA is up-regulated due to increased stability when estrogen negatively controls mevalonate kinase	Rattus norvegicus

Inhibitors

Inhibitors	Comment	Organism	Structure
estradiol	together with follicle-stimulating hormone, decreases mevalonate kinase mRNA levels, resulting in up-regulation of luteinizing hormone receptor mRNA that is inversely correlated to mevalonate kinase mRNA expression	Rattus norvegicus
follicle-stimulating hormone	together with estradiol, decreases mevalonate kinase mRNA levels, resulting in up-regulation of luteinizing hormone receptor mRNA that is inversely correlated to mevalonate kinase mRNA expression	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
granulosa cell	cultured cell	Rattus norvegicus	-

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Release 2023.1 (January 2023)