Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + phosphoenolpyruvate | - |
Mus musculus | ATP + pyruvate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
M2-PK | - |
Mus musculus |
pyruvate kinase M2 | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | tumor-associated dendritic cells with higher levels of SOCS3 have reduced M2-PK activity | down |
General Information | Comment | Organism |
---|---|---|
physiological function | suppressor of cytokine signaling 3 interacts with M2-PK to decrease ATP production causing dendritic cell dysfunction | Mus musculus |