Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | the majority of PKM2 protein localizes to the cytoplasm, especially in the perinuclear region | Mus musculus | 5737 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
62000 | - |
SDS-PAGE | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
embryonic stem cell | - |
Mus musculus | - |
additional information | M2-PK is specifically expressed in proliferating cells, such as embryonic stem cells, embryonic carcinoma cells, as well as cancer cells | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ADP + phosphoenolpyruvate | - |
Mus musculus | ATP + pyruvate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
M2-PK | - |
Mus musculus |
PKM2 | - |
Mus musculus |
pyruvate kinase isozyme type M2 | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ADP | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | Oct-4-mediated transcriptional activity is positively regulated by PKM2 | Mus musculus |