Literature summary for 2.7.1.67 extracted from

Jenkins, G.H.; Subrahmanyam, G.; Anderson, R.A.
Purification and reconstitution of phosphatidylinositol 4-kinase from human erythrocytes (1991), Biochim. Biophys. Acta, 1080, 11-18.

Search for more literature for 2.7.1.67

Activating Compound

Activating Compound	Comment	Organism	Structure
Dimethylsulfoxide	1.0%, activation to 160% of the original activity	Homo sapiens
heparin	0.01 mM, activation to 116% of the orginal activity	Homo sapiens
spermine	2.0 mM, activation to 121% of the original activity	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
PCMB	0.01 mM, 74% inhibition	Homo sapiens

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.035	-	ATP	pH 7.5, 30°C	Homo sapiens
0.04	-	phosphatidylinositol	pH 7.5, 30°C	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	bound to	Homo sapiens	16020	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
59000	-	x * 59000, SDS-PAGE	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
erythrocyte	-	Homo sapiens	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.044	-	-	Homo sapiens

Storage Stability

Storage Stability	Organism
-20°C, 50% glycerol, stable for 4 weeks	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + 1-phosphatidyl-1D-myo-inositol	-	Homo sapiens	ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate	-	?

Subunits

Subunits	Comment	Organism
?	x * 59000, SDS-PAGE	Homo sapiens

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Release 2023.1 (January 2023)