Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.7.10.1 extracted from

  • Canfield, K.; Li, J.; Wilkins, O.; Morrison, M.; Ung, M.; Wells, W.; Williams, C.; Liby, K.; Vullhorst, D.; Buonanno, A.; Hu, H.; Schiff, R.; Cook, R.; Kurokawa, M.
    Receptor tyrosine kinase ERBB4 mediates acquired resistance to ERBB2 inhibitors in breast cancer cells (2015), Cell Cycle, 14, 648-655.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.10.1

Inhibitors

Inhibitors Comment Organism Structure
1,4-diamino-2,3-dicyano-1,4-bis(2-aminophenylthio)-butadiene
-
 Homo sapiens
afatinib
-
 Homo sapiens
BI2536
-
 Homo sapiens
canertinib
-
 Homo sapiens
crizotinib
-
 Homo sapiens
dacomitinib
-
 Homo sapiens
dasatinib
-
 Homo sapiens
erlotinib
-
 Homo sapiens
gefitinib
-
 Homo sapiens
imatinib
-
 Homo sapiens
KU55933
-
 Homo sapiens
lapatinib dual inhibitor of EGFR and ERBB2 Homo sapiens
LY2874455
-
 Homo sapiens
neratinib
-
 Homo sapiens
NVP-BEZ235
-
 Homo sapiens
PD184352
-
 Homo sapiens
PD325901
-
 Homo sapiens
PD98059
-
 Homo sapiens
PIK-90
-
 Homo sapiens
PI_103
-
 Homo sapiens
sorafenib
-
 Homo sapiens
staurosporine
-
 Homo sapiens
trastuzumab
-
 Homo sapiens
tyrphostin
-
 Homo sapiens
varlitinib
-
 Homo sapiens
ZSTK474
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
BT474 cell
-
 Homo sapiens
-
BT474-LR cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
Egfr
-
 Homo sapiens
ErbB2
-
 Homo sapiens
ErbB4
-
 Homo sapiens
HER2
-
 Homo sapiens
HER4
-
 Homo sapiens

General Information

General Information Comment Organism
physiological function ERBB4 plays a key role in the survival of ERBB2C cancer cells after they develop resistance to ERBB2 inhibitors, lapatinib and trastuzumab Homo sapiens