Cloned (Comment) | Organism |
---|---|
transient overexpression of the GFP-tagged wild-type Chk and the N-terminal domain, as well as of the inactivated enzyme mutant, in HeLa cells and COS-1 cells, overexpression of the enzyme leads to increased tyrosine phosphorylation of protein especially from the nuclear matrix, expression and subcellular localization analysis, overview | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | the N-terminal domain of Chk is associated with the nucleus and the nuclear matrix | Homo sapiens | 5634 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme tyrosine phosphorylates a wide range of proteins, especially nuclear matrix proteins | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme tyrosine phosphorylates a wide range of proteins, especially nuclear matrix proteins | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Chk tyrosine kinase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens |