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Literature summary for 2.7.10.2 extracted from

  • Liang, Y.; Jin, Y.; Li, Y.
    Expression of JAKs/STATs pathway molecules in rat model of rapid focal segmental glomerulosclerosis (2009), Pediatr. Nephrol., 24, 1661-1671.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
kidney
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Rattus norvegicus
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Synonyms

Synonyms Comment Organism
JAK
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Rattus norvegicus
Janus kinase
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Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus at the mRNA level, JAK1 is significantly increased in rats with nephropathy induced by unilateral nephrectomy and a single tail vein injection of adriamycin (5 mg/kg) in week 2, whereas JAK2 mRNA shows a significant decrease by weeks 2 and 4, followed by an significant increase in week 6 up