Literature summary for 2.7.10.2 extracted from

Moody, T.W.; Di Florio, A.; Jensen, R.T.
PYK-2 is tyrosine phosphorylated after activation of pituitary adenylate cyclase activating polypeptide receptors in lung cancer cells (2012), J. Mol. Neurosci., 48, 660-666.

Search for more literature for 2.7.10.2

Activating Compound

Activating Compound	Comment	Organism	Structure
Ca2+	G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q14289	PYK2	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
phosphoprotein	G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C	Homo sapiens

Synonyms

Synonyms	Comment	Organism
Pyk2	-	Homo sapiens

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Release 2023.1 (January 2023)