Literature summary for 2.7.10.2 extracted from

Toubiana, J.; Rossi, A.L.; Belaidouni, N.; Grimaldi, D.; Pene, F.; Chafey, P.; Comba, B.; Camoin, L.; Bismuth, G.; Claessens, Y.E.; Mira, J.P.; Chiche, J.D.
Src-family-tyrosine kinase Lyn is critical for TLR2-mediated NF-kappaB activation through the PI 3-kinase signaling pathway (2015), Innate Immun., 21, 685-697.

Search for more literature for 2.7.10.2

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + [p110 catalytic subunit of PI 3-kinase]-L-tyrosine	Homo sapiens	-	ADP + [p110 catalytic subunit of PI 3-kinase]-L-tyrosine phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
mononuclear cell	-	Homo sapiens	-
THP-1 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + [p110 catalytic subunit of PI 3-kinase]-L-tyrosine	-	Homo sapiens	ADP + [p110 catalytic subunit of PI 3-kinase]-L-tyrosine phosphate	-	?

Synonyms

Synonyms	Comment	Organism
Lyn	-	Homo sapiens

General Information

General Information	Comment	Organism
physiological function	tyrosine kinase Lyn is critical for TLR2-mediated NF-kappaB activation through the PI 3-kinase signaling pathway	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)