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Literature summary for 2.7.10.2 extracted from
- The tyrosine kinase c-Src specifically binds to the active integrin alphaIIbbeta3 to initiate outside-in signaling in platelets (2015), J. Biol. Chem., 290, 15825-15834.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli BL21-Codon-Plus(DE3) cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| HisTrap column chromatography | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | after platelet stimulation, integrin alphaIIbbeta3 binds to the enzyme's SH3 domain at a site overlapping with its PPII helix binding site | Homo sapiens | ? | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| C-SRC | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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