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Literature summary for 2.7.10.2 extracted from

  • Francis, K.R.; Wei, L.; Yu, S.P.
    Src tyrosine kinases regulate neuronal differentiation of mouse embryonic stem cells via modulation of voltage-gated sodium channel activity (2015), Neurochem. Res., 40, 674-687.
    View publication on PubMed
Search for more literature for 2.7.10.2

Inhibitors

Inhibitors Comment Organism Structure
4-amino-5-(4-chlorophenyl)-7-(t-butyl) pyrazolo[3,4-d]pyrimidine
-
 Mus musculus
SU6656
-
 Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + a [protein]-L-tyrosine Mus musculus
-
 ADP + a [protein]-L-tyrosine phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryonic stem cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a [protein]-L-tyrosine
-
 Mus musculus ADP + a [protein]-L-tyrosine phosphate
-
 ?

Synonyms

Synonyms Comment Organism
SFK
-
 Mus musculus
Src tyrosine kinase
-
 Mus musculus

General Information

General Information Comment Organism
physiological function the enzyme influences neuronal differentiation via a chronic regulation of Na+ channel functionality. The tonic enzyme activity is also critical for normal development of functional Na+ channels and neuronal differentiation or maturation of embryonic stem cells Mus musculus