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Literature summary for 2.7.11.1 extracted from

  • Flaggs, G.; Plug, A.W.; Dunks, K.M.; Mundt, K.E.; Ford, J.C.; Quiggle, M.R.; Taylor, E.M.; Westphal, C.H.; Ashley, T.; Hoekstra, M.F.; Carr, A.M.
    Atm-dependent interactions of a mammalian chk1 homolog with meiotic chromosomes (1997), Curr. Biol., 7, 977-986.
    View publication on PubMed
Search for more literature for 2.7.11.1

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens Chk1 acts as an integrator for Atm and Atr signals and may be involved in monitoring the processing of meiotic recombination CHK1 gene is a candidate tumor suppressor gene ?
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 ?
additional information Mus musculus Chk1 acts as an integrator for Atm and Atr signals and may be involved in monitoring the processing of meiotic recombination CHK1 gene is a candidate tumor suppressor gene ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens O14757
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-
Mus musculus O35280
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-

Source Tissue

Source Tissue Comment Organism Textmining
testis accumulates in late zygotene and pachytene spermatocytes and is present along synapsed meiotic chromosomes, localizes along the unsynapsed axes of X and Y chromosomes in pachytene spermatocytes Homo sapiens
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testis accumulates in late zygotene and pachytene spermatocytes and is present along synapsed meiotic chromosomes, localizes along the unsynapsed axes of X and Y chromosomes in pachytene spermatocytes Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information Chk1 acts as an integrator for Atm and Atr signals and may be involved in monitoring the processing of meiotic recombination CHK1 gene is a candidate tumor suppressor gene Homo sapiens ?
-
 ?
additional information Chk1 acts as an integrator for Atm and Atr signals and may be involved in monitoring the processing of meiotic recombination CHK1 gene is a candidate tumor suppressor gene Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
Chk1
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 Homo sapiens
serine/threonine-protein kinase Chk1
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 Homo sapiens
serine/threonine-protein kinase Chk1
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 Mus musculus