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Literature summary for 2.7.11.1 extracted from

  • Roosbeek, S.; Peelman, F.; Verhee, A.; Labeur, C.; Caster, H.; Lensink, M.F.; Cirulli, C.; Grooten, J.; Cochet, C.; Vandekerckhove, J.; Amoresano, A.; Chimini, G.; Tavernier, J.; Rosseneu, M.
    Phosphorylation by protein kinase CK2 modulates the activity of the ATP binding cassette A1 transporter (2004), J. Biol. Chem., 279, 37779-37788.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression of CK2 alpha and beta subunits in Spodoptera frugiperda Sf9 cells via baculovirus transfection system Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant CK2 from insect Sf9 cells to homogeneity Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + ABCA1 NBD1-R1 protein substrate protein is a recombinant construct of wild-type and mutant nucleotide binding domain 1 and cytoplasmic domain R1 of ATP-binding cassette transporter protein A1 expressed in Escherichia coli, phosphorylation at T1242, T1243, and S1255 Homo sapiens ADP + phosphorylated ABCA1 NBD1-R1 protein
-
?
ATP + ABCA1 NBD2-R2 protein substrate protein is a recombinant construct of wild-type and mutant nucleotide binding domain 2 and cytoplasmic domain R2 of ATP-binding cassette transporter protein A1 expressed in Escherichia coli Homo sapiens ADP + phosphorylated ABCA1 NBD2-R2 protein
-
?
additional information substrate ABC transporter protein structure, phosphorylation of the ABCA1 transporter reduces its flippase activity, overview Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
casein kinase 2
-
Homo sapiens
CK2
-
Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
22
-
assay at Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ATP
-
Homo sapiens