Literature summary for 2.7.13.3 extracted from

Rasmussen, B.A.; Kovacs, E.
Cloning and identification of a two-component signal-transducing regulatory system from Bacteroides fragilis (1993), Mol. Microbiol., 7, 765-776.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression of these proteins from a multicopy plasmid vector in Escherichia coli	Bacteroides fragilis

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + a protein	Bacteroides fragilis	regulation of the levels of OmpF and OmpC is normally controlled by a multicomponent signal-transducing regulatory pair of proteins, EnvZ and OmpR. The effect RprX and RprY have on OmpF expression is mediated at the level of transcription. Thus, RprX and RprY may be interfering with the normal regulation of OmpF by OmpR and EnvZ	ADP + a phosphoprotein	-	?

Organism

Organism	UniProt	Comment	Textmining
Bacteroides fragilis	Q08408	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + a protein	regulation of the levels of OmpF and OmpC is normally controlled by a multicomponent signal-transducing regulatory pair of proteins, EnvZ and OmpR. The effect RprX and RprY have on OmpF expression is mediated at the level of transcription. Thus, RprX and RprY may be interfering with the normal regulation of OmpF by OmpR and EnvZ	Bacteroides fragilis	ADP + a phosphoprotein	-	?

Synonyms

Synonyms	Comment	Organism
sensor protein rprX	-	Bacteroides fragilis

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Release 2023.1 (January 2023)