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Literature summary for 2.7.4.2 extracted from

  • Hogenboom, S.; Tuyp, J.J.; Espeel, M.; Koster, J.; Wanders, R.J.; Waterham, H.R.
    Phosphomevalonate kinase is a cytosolic protein in humans (2004), J. Lipid Res., 45, 697-705.
    View publication on PubMed
Search for more literature for 2.7.4.2

Cloned(Commentary)

Cloned (Comment) Organism
expressed in CV-1 cells Homo sapiens
expression in human embryonic kidney (HEK-293) Flp-In and CV1 cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + (R)-5-phosphomevalonate Homo sapiens mevalonate pathway of isopentenyl diphosphate biosynthesis ADP + (R)-5-diphosphomevalonate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
fibroblast endogenously expressed human phosphomevalonate kinase and overexpressed human phosphomevalonate kinase Homo sapiens
-
HEK-293 cell endogenously expressed human phosphomevalonate kinase and overexpressed human phosphomevalonate kinase Homo sapiens
-
liver endogenously expressed human phosphomevalonate kinase Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (R)-5-phosphomevalonate mevalonate pathway of isopentenyl diphosphate biosynthesis Homo sapiens ADP + (R)-5-diphosphomevalonate
-
 ?

Synonyms

Synonyms Comment Organism
phosphomevalonate kinase
-
 Homo sapiens
PMK
-
 Homo sapiens