Literature summary for 2.7.4.2 extracted from

Boonsri, P.; Neumann, T.S.; Olson, A.L.; Cai, S.; Herdendorf, T.J.; Miziorko, H.M.; Hannongbua, S.; Sem, D.S.
Molecular docking and NMR binding studies to identify novel inhibitors of human phosphomevalonate kinase (2013), Biochem. Biophys. Res. Commun., 430, 313-319.

Search for more literature for 2.7.4.2

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21 (DE3) Rosetta cells	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
2,2',2''-(biphenyl-2,4,6-triyltrisulfanediyl)triacetate	-	Homo sapiens
2,2'-[(5,8-dihydroxy-9,10-dioxo-4a,9,9a,10-tetrahydroanthracene-1,4-diyl)diimino]bis(5-methylbenzenesulfonate)	-	Homo sapiens
4-[(E)-(2,4-dihydroxyphenyl)diazenyl]-5-methylnaphthalene-2,7-disulfonate	-	Homo sapiens
luteolin	-	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
22000	-	x * 22000, SDS-PAGE	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q15126	-	-

Purification (Commentary)

Purification (Comment)	Organism
Ni-Sepharose column chromatography	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + (R)-5-phosphomevalonate	-	Homo sapiens	ADP + (R)-5-diphosphomevalonate	-	?

Subunits

Subunits	Comment	Organism
?	x * 22000, SDS-PAGE	Homo sapiens

Synonyms

Synonyms	Comment	Organism
PMK	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)