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Literature summary for 2.7.4.3 extracted from
- Adenylate kinase 2 (AK2) promotes cell proliferation in insect development (2012), BMC Mol. Biol., 13, 31.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Helicoverpa armigera |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Helicoverpa armigera | 5739 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required | Helicoverpa armigera |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 27000 | - |
x * 27000, calculated from amino acid sequence | Helicoverpa armigera |
| 33000 | - |
x * 33000, His-tagged enzyme, SDS-PAGE | Helicoverpa armigera |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Helicoverpa armigera | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adipose tissue | - |
Helicoverpa armigera | - |
| epidermal cell | - |
Helicoverpa armigera | - |
| epidermis | - |
Helicoverpa armigera | - |
| HaEpi cell | - |
Helicoverpa armigera | - |
| hemocyte | - |
Helicoverpa armigera | - |
| larva | - |
Helicoverpa armigera | - |
| midgut | - |
Helicoverpa armigera | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + AMP | - |
Helicoverpa armigera | 2 ADP | - |
r | |
| GTP + AMP | - |
Helicoverpa armigera | GDP + ADP | - |
r | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 27000, calculated from amino acid sequence | Helicoverpa armigera |
| ? | x * 33000, His-tagged enzyme, SDS-PAGE | Helicoverpa armigera |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| adenylate kinase 2 | - |
Helicoverpa armigera |
| AK2 | - |
Helicoverpa armigera |
pI Value
| Organism | Comment | pI Value Maximum | pI Value |
|---|---|---|---|
| Helicoverpa armigera | calculated from amino acid sequence | - |
8.9 |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | adenylate kinase 2 knockdown in larvae by RNA interference causes larval growth defects, including body weight decrease and development delay. Adenylate kinase 2 knockdown in larvae also decreases the number of circulating hemocytes | Helicoverpa armigera |
| physiological function | adenylate kinase 2 regulates cell growth, viability, and proliferation in insect growth and development | Helicoverpa armigera |
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