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Literature summary for 2.7.6.4 extracted from

  • Nishino, T.; Murao, S.
    Characterization of pyrophosphoryl transfer reaction of ATP:nucleotide pyrophosphotransferase (1975), Agric. Biol. Chem., 39, 1007-1014.
No PubMed abstract available
Search for more literature for 2.7.6.4

Metals/Ions

Metals/Ions Comment Organism Structure
Co2+ absolute requirement for bivalent cations, at pH 10.0 Mg2+ is most effective, while Mn2+, Co2+ and Zn2+ show little activity. At pH 7.0, Co2+ is most effective and Mg2+, Mn2+, Ni2+ and Fe2+ show little activity. Optimal concentration is 2.5 mM Co2+ Streptomyces adephospholyticus
Fe2+ absolute requirement for bivalent cations, at pH 10.0 Mg2+ is most effective, while Mn2+, Co2+ and Zn2+ show little activity. At pH 7.0, Co2+ is most effective and Mg2+, Mn2+, Ni2+ and Fe2+ show little activity Streptomyces adephospholyticus
Mg2+ absolute requirement for bivalent cations, at pH 10.0, Mg2+ is most effective, while Mn2+, Co2+ and Zn2+ show little activity. At pH 7.0, Co2+ is most effective and Mg2+, Mn2+, Ni2+ and Fe2+ show little activity. Optimal concentration is 5 mM Mg2+ Streptomyces adephospholyticus
Mn2+ absolute requirement for bivalent cations, at pH 10.0 Mg2+ is most effective, while Mn2+, Co2+ and Zn2+ show little activity. At pH 7.0, Co2+ is most effective and Mg2+, Mn2+, Ni2+ and Fe2+ show little activity Streptomyces adephospholyticus
Ni2+ absolute requirement for bivalent cations, at pH 10.0 Mg2+ is most effective, while Mn2+, Co2+ and Zn2+ show little activity. At pH 7.0, Co2+ is most effective and Mg2+, Mn2+, Ni2+ and Fe2+ show little activity Streptomyces adephospholyticus

Organism

Organism UniProt Comment Textmining
Streptomyces adephospholyticus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + ADP
-
 Streptomyces adephospholyticus AMP + adenosine 3'-diphosphate 5'-diphosphate
-
 ?
ATP + AMP
-
 Streptomyces adephospholyticus AMP + adenosine 3'-phosphate 5'-diphosphate
-
 ?
ATP + GDP
-
 Streptomyces adephospholyticus AMP + guanosine 3'-diphosphate 5'-diphosphate
-
 ?
ATP + GMP
-
 Streptomyces adephospholyticus AMP + guanosine 3'-phosphate 5'-diphosphate
-
 ?
ATP + GTP
-
 Streptomyces adephospholyticus AMP + guanosine-3'-diphosphate-5'-triphosphate
-
 ?
ATP + IDP
-
 Streptomyces adephospholyticus AMP + inosine 3'-diphosphate 5'-diphosphate
-
 ?
ATP + IMP
-
 Streptomyces adephospholyticus AMP + inosine 3'-diphosphate 5'-phosphate
-
 ?
ATP + ITP
-
 Streptomyces adephospholyticus AMP + inosine 3'-diphosphate 5'-triphosphate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5 8 synthesis of A5P, with Co2+ as activating cation Streptomyces adephospholyticus
9.5 10 Mg2+ as activating cation Streptomyces adephospholyticus