Literature summary for 2.7.7.4 extracted from

MacRae, I.J.; Segel, I.H.; Fisher, A.J.
Allosteric inhibition via R-state destabilization in ATP sulfurylase from Penicillium chrysogenum (2002), Nat. Struct. Biol., 9, 945-949.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
recombinant enzyme expressed in Escherichia coli, crystals are grown at 22°C by vapor diffusion in hanging drops, crystal structure of the enzyme bound to the allosteric inhibitor 3'-phosphoadenosine-5'-phosphosulfate determined at 2.6 A resolution	Penicillium chrysogenum

Inhibitors

Inhibitors	Comment	Organism	Structure
3'-phosphoadenosine-5'-phosphate	allosteric	Penicillium chrysogenum

Organism

Organism	UniProt	Comment	Textmining
Penicillium chrysogenum	Q12650	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + sulfate	-	Penicillium chrysogenum	diphosphate + adenylylsulfate	-	r

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Release 2023.1 (January 2023)