Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma brucei brucei | Q57U32 | - |
- |
Trypanosoma brucei brucei 927 / 4 GUTat10.1 / TREU927 | Q57U32 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
Tb927.7.220 | - |
Trypanosoma brucei brucei |
General Information | Comment | Organism |
---|---|---|
physiological function | CDS gene expression is essential in the bloodstream form of the parasite. A CDS conditional knockout shows morphological changes including a cell-cycle arrest due in part to kinetoplast segregation defects. The conditional knockout shows drastically altered lipid metabolism where reducing levels of phosphatidylinositol detrimentally impact on glycoylphosphatidylinositol biosynthesis. Expression of Trypanosoma brucei CDS gene complements a non-viable yeast CDS null strain | Trypanosoma brucei brucei |