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Literature summary for 2.7.7.48 extracted from

  • Sun, A.; Chandrakumar, N.; Yoon, J.J.; Plemper, R.K.; Snyder, J.P.
    Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex activity: Synthesis and in vitro evaluation (2007), Bioorg. Med. Chem. Lett., 17, 5199-5203.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.48

Inhibitors

Inhibitors Comment Organism Structure
(2S)-1-[[4-([[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]carbonyl]amino)phenyl]sulfonyl]pyrrolidine-2-carboxylic acid
-
 Measles morbillivirus
1,3-dimethyl-N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]-1H-pyrazole-5-carboxamide
-
 Measles morbillivirus
1-methyl-3-(trifluoromethyl)-N-[4-(pyrrolidinylsulfonyl)phenyl]-1H-pyrazole-5-carboxamide
-
 Measles morbillivirus
1-methyl-5-[[4-(pyrrolidin-1-ylsulfonyl)phenoxy]methyl]-3-(trifluoromethyl)-1H-pyrazole
-
 Measles morbillivirus
1-methyl-N-[4-(morpholin-4-ylsulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
-
 Measles morbillivirus
1-methyl-N-[4-(piperazin-1-ylsulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
-
 Measles morbillivirus
1-methyl-N-[4-(piperidin-1-ylsulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
-
 Measles morbillivirus
1-phenyl-N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
-
 Measles morbillivirus
1-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]-2-[4-(pyrrolidin-1-ylsulfonyl)phenyl]ethanol
-
 Measles morbillivirus
1-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]-2-[4-(pyrrolidin-1-ylsulfonyl)phenyl]ethanone
-
 Measles morbillivirus
1-[[4-([[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]carbonyl]amino)phenyl]sulfonyl]piperidine-2-carboxylic acid
-
 Measles morbillivirus
2-([[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]carbonyl]amino)-5-(pyrrolidin-1-ylsulfonyl)phenyl 1-methyl-3-(trifluoromethyl)-1H-pyrazole-5-carboxylate
-
 Measles morbillivirus
2-bromo-5-methoxy-N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]benzamide
-
 Measles morbillivirus
2-chloro-4-nitro-N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]benzamide
-
 Measles morbillivirus
2-fluoro-N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]-5-(trifluoromethyl)benzamide
-
 Measles morbillivirus
2-methyl-N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]-6-(trifluoromethyl)pyridine-3-carboxamide
-
 Measles morbillivirus
2-nitro-N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]-4-(trifluoromethyl)benzamide
-
 Measles morbillivirus
3-tert-butyl-1-methyl-N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]-1H-pyrazole-5-carboxamide
-
 Measles morbillivirus
4-(chloromethyl)-N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]benzamide
-
 Measles morbillivirus
4-amino-2-chloro-N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]benzamide
-
 Measles morbillivirus
4-bromo-N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]benzamide
-
 Measles morbillivirus
4-fluoro-N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]benzamide
-
 Measles morbillivirus
N,N'-[4-(pyrrolidin-1-ylsulfonyl)benzene-1,2-diyl]bis[1-methyl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide]
-
 Measles morbillivirus
N-[2-amino-4-(pyrrolidin-1-ylsulfonyl)phenyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
-
 Measles morbillivirus
N-[2-hydroxy-4-(pyrrolidin-1-ylsulfonyl)phenyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
-
 Measles morbillivirus
N-[4-(1H-indol-1-ylsulfonyl)phenyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
-
 Measles morbillivirus
N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]-1,3-benzothiazole-2-carboxamide
-
 Measles morbillivirus
N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]-1-[2-(trifluoromethyl)phenyl]-1H-imidazole-2-carboxamide
-
 Measles morbillivirus
N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]-2-(trifluoromethyl)benzamide
-
 Measles morbillivirus
N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]-3-(trifluoromethyl)benzamide
-
 Measles morbillivirus
N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]-4-(trifluoromethyl)benzamide
-
 Measles morbillivirus
N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]furan-2-carboxamide
-
 Measles morbillivirus
N-[4-(pyrrolidin-1-ylsulfonyl)phenyl]thiophene-2-carboxamide
-
 Measles morbillivirus
N-[[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]methyl]-4-(pyrrolidin-1-ylsulfonyl)aniline
-
 Measles morbillivirus
phenyl 1-[[4-([[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]carbonyl]amino)phenyl]sulfonyl]-L-prolinate
-
 Measles morbillivirus

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Measles morbillivirus
-
-
-
Measles morbillivirus Alaska
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
nucleoside triphosphate + RNAn
-
 Measles morbillivirus diphosphate + RNAn+1
-
 ?
nucleoside triphosphate + RNAn
-
 Measles morbillivirus Alaska diphosphate + RNAn+1
-
 ?

Synonyms

Synonyms Comment Organism
RDRP
-
 Measles morbillivirus
RNA-dependent RNA polymerase
-
 Measles morbillivirus