Literature summary for 2.7.7.6 extracted from

Garro, H.A.; Garcia, C.; Martin, V.S.; Tonn, C.E.; Pungitore, C.R.
A new iridoid, verbascoside and derivatives with inhibitory activity against Taq DNA polymerase (2015), Bioorg. Med. Chem. Lett., 25, 914-918.

Search for more literature for 2.7.7.6

Inhibitors

Inhibitors	Comment	Organism	Structure
6,10,6'-tri-O-tert-butyldimethylsilyl-6-epi-catalpol	-	Thermus aquaticus
per-O-acetyl-verbascoside	compound isolated from aerial part of Buddleja cordobensis Grisebach, most active among the compounds tested	Thermus aquaticus

Organism

Organism	UniProt	Comment	Textmining
Thermus aquaticus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
commercial preparation	-	Thermus aquaticus	-

Synonyms

Synonyms	Comment	Organism
Taq polymerase	-	Thermus aquaticus

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0012	-	pH 8.3, 72°C	Thermus aquaticus	per-O-acetyl-verbascoside
0.0056	-	pH 8.3, 72°C	Thermus aquaticus	6,10,6'-tri-O-tert-butyldimethylsilyl-6-epi-catalpol

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)