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Literature summary for 2.7.7.65 extracted from

  • O'Shea, T.M.; Klein, A.H.; Geszvain, K.; Wolfe, A.J.; Visick, K.L.
    Diguanylate cyclases control magnesium-dependent motility of Vibrio fischeri (2006), J. Bacteriol., 188, 8196-8205.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.65

Cloned(Commentary)

Cloned (Comment) Organism
expression of MifA or MifB by medium-copy plasmids inhibits motility of Vibrio fischeri. Expression by multicopy plasmids induces further phenotypes correlated with diguanylate cyclase activity such as cellulose biosynthesis and biofilm formation. High-copy expression in Escherichia coli Aliivibrio fischeri

Protein Variants

Protein Variants Comment Organism
additional information enzyme disruption mutants of MifA or MifB show increased flagellin levels, while mutlicopy expression decreases them Aliivibrio fischeri

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane both MifA and MifB are membrane-associated Aliivibrio fischeri 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Aliivibrio fischeri MifA and MifB proteins act posttranscriptionally on flagellation ?
-
 ?

Organism

Organism UniProt Comment Textmining
Aliivibrio fischeri
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP
-
 Aliivibrio fischeri cyclic di-3',5'-guanylate + diphosphate
-
 ?
additional information MifA and MifB proteins act posttranscriptionally on flagellation Aliivibrio fischeri ?
-
 ?

Synonyms

Synonyms Comment Organism
MifA
-
 Aliivibrio fischeri
MifB
-
 Aliivibrio fischeri