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Literature summary for 2.7.7.65 extracted from

  • Enomoto, G.; Nomura, R.; Shimada, T.; Ni-Ni-Win, T.; Narikawa, R.; Ikeuchi, M.
    Cyanobacteriochrome SesA is a diguanylate cyclase that induces cell aggregation in Thermosynechococcus (2014), J. Biol. Chem., 289, 24801-24809.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.65

Cloned(Commentary)

Cloned (Comment) Organism
expression in a cyanobacterial system Thermosynechococcus vestitus

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required for diguanylate cyclase activity, Kd value 10.5 mM Thermosynechococcus vestitus

Organism

Organism UniProt Comment Textmining
Thermosynechococcus vestitus Q8DKD5
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 GTP
-
 Thermosynechococcus vestitus 2 diphosphate + cyclic di-3',5'-guanylate conversion is enhanced under blue light irradiation, with 38fold difference between the blue and green light-induced activities ?
additional information no substrate: ATP Thermosynechococcus vestitus ?
-
 ?

Subunits

Subunits Comment Organism
More protein contains a GGDEFdomain Thermosynechococcus vestitus

Synonyms

Synonyms Comment Organism
SesA
-
 Thermosynechococcus vestitus
Tlr0924
-
 Thermosynechococcus vestitus

General Information

General Information Comment Organism
physiological function the protein reversibly photoconverts between blue- and green-absorbing forms, and has diguanylate cyclase activity, which is enhanced 38fold by blue light compared with green light. The protein's relatively low affinity for Mg2+, which is essential for diguanylate cyclase activity, suggests thatMg2might also regulate cyclic-di-GMP signaling. Blue light irradiation under low temperature is responsible for Thermosynechococcus vulcanus cell aggregation, which is abolished when gene Tlr0924 is disrupted Thermosynechococcus vestitus