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Literature summary for 2.7.7.7 extracted from

  • Peck, V.M.; Germer, E.W.; Cress, A.E.
    delta-type DNA polymerase characterized from Drosophila melanogaster embryos (1992), Nucleic Acids Res., 20, 5779-5784.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
proliferating cell nuclear antigen
-
Drosophila melanogaster

General Stability

General Stability Organism
highly sensitive to freezing and thawing Drosophila melanogaster

Inhibitors

Inhibitors Comment Organism Structure
aphidicolin inhibition at 0.01 and 0.1 mg/ml Drosophila melanogaster
Dideoxythymidine triphosphate inhibition at 0.05 mM Drosophila melanogaster
KCl inhibition at 0.2 mM Drosophila melanogaster
N2-(p-n-butylphenyl)-2'-deoxyguanosine 5'-triphosphate inhibition at 0.1 mM Drosophila melanogaster

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
deoxynucleoside triphosphate + DNAn Drosophila melanogaster
-
diphosphate + DNAn+1
-
?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
-
-

Purification (Commentary)

Purification (Comment) Organism
alpha and delta-type polymerases Drosophila melanogaster

Source Tissue

Source Tissue Comment Organism Textmining
embryo
-
Drosophila melanogaster
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.59
-
-
Drosophila melanogaster

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxynucleoside triphosphate + DNAn
-
Drosophila melanogaster diphosphate + DNAn+1
-
?