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Literature summary for 2.7.7.7 extracted from

  • Jiang, Q.; Karata, K.; Woodgate, R.; Cox, M.M.; Goodman, M.F.
    The active form of DNA polymerase V is UmuD(2)C-RecA-ATP (2009), Nature, 460, 359-363.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
RecA DNA polymerase V is activated by a RecA nucleoprotein filament, RecA transfers a single RecA-ATP stoichiometrically from its DNA 3'-end to free pol V (UmuD'2C) to form an active mutasome with the composition UmuD'2C-RecA-ATP Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
deoxynucleoside triphosphate + DNAn
-
Escherichia coli diphosphate + DNAn+1
-
?

Synonyms

Synonyms Comment Organism
DNA polymerase V
-
Escherichia coli
Pol V
-
Escherichia coli
UmuD'2C free DNA polymerase V Escherichia coli
UmuD'2C-RecA-ATP active form of DNA polymerase V Escherichia coli