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Literature summary for 2.7.7.7 extracted from

  • Zhang, H.; Beckman, J.W.; Guengerich, F.P.
    Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation (2009), J. Biol. Chem., 284, 35144-35153.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.7.7

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Saccharolobus solfataricus

Protein Variants

Protein Variants Comment Organism
T239W the frameshift deletion is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation Saccharolobus solfataricus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information steady-state kinetic parameters for the single dNTP incorporation by Dpo4 T239W Saccharolobus solfataricus

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus
-
-
-
Saccharolobus solfataricus P2
-
-
-

Synonyms

Synonyms Comment Organism
DNA polymerase Dpo4
-
 Saccharolobus solfataricus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
 additional information steady-state kinetic parameters for the single dNTP incorporation by Dpo4 T239W Saccharolobus solfataricus

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
additional information
-
 additional information steady-state kinetic parameters for the single dNTP incorporation by Dpo4 T239W Saccharolobus solfataricus