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Literature summary for 2.7.8.1 extracted from
- Control of phosphatidylethanolamine metabolism in yeast: diacylglycerol ethanolaminephosphotransferase and diacylglycerol cholinephosphotransferase are separate enzymes (1984), Arch. Biochem. Biophys., 230, 69-81.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| 1,2-diacylglycerol | stimulated by exogenous 1,2-diacylglycerols, largest stimulation by 1,2-diolein and 1,2-diacylglycerol | Saccharomyces cerevisiae |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,2-Dilaurin | slight | Saccharomyces cerevisiae | |
| 5'-AMP | slight | Saccharomyces cerevisiae | |
| 5'-CMP | - |
Saccharomyces cerevisiae | |
| 5'-GMP | slight | Saccharomyces cerevisiae | |
| 5'-UMP | slight | Saccharomyces cerevisiae | |
| CDP | - |
Saccharomyces cerevisiae | |
| CMP | - |
Saccharomyces cerevisiae | |
| CTP | - |
Saccharomyces cerevisiae | |
| DH-990 | hypolidemic drug | Saccharomyces cerevisiae | |
| p-hydroxymercuribenzoate | reversal by monothioglycerol | Saccharomyces cerevisiae | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.083 | - |
CDP-ethanolamine | 37°C, pH 8.0 | Saccharomyces cerevisiae | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| membrane | - |
Saccharomyces cerevisiae | 16020 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mn2+ | required | Saccharomyces cerevisiae | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| CDP-ethanolamine + 1,2-diacylglycerol | in presence of 5'-CMP | Saccharomyces cerevisiae | CMP + a phosphatidylethanolamine | - |
r | |
| CDP-ethanolamine + 1,2-dioleoylglycerol | - |
Saccharomyces cerevisiae | CMP + dioleoylphosphatidylethanolamine | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 30 | 37 | - |
Saccharomyces cerevisiae |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | - |
t1/2: 8 min | Saccharomyces cerevisiae |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
- |
Saccharomyces cerevisiae |
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