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Literature summary for 2.7.8.11 extracted from

  • Elabbadi, N.; Ancelin, M.L.; Vial, H.J.
    Characterization of phosphatidylinositol synthase and evidence of a polyphosphoinositide cycle in Plasmodium-infected erythrocytes (1994), Mol. Biochem. Parasitol., 63, 179-192.
    View publication on PubMed
Search for more literature for 2.7.8.11

Inhibitors

Inhibitors Comment Organism Structure
Ca2+ inhibition above 2 mM Plasmodium knowlesi

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.16
-
 CDP-diacylglycerol
-
 Plasmodium knowlesi
1
-
 myo-inositol
-
 Plasmodium knowlesi

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Plasmodium knowlesi 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Plasmodium knowlesi
Mn2+
-
 Plasmodium knowlesi
additional information Ca2+ is ineffective Plasmodium knowlesi

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
CDP-diacylglycerol + myo-inositol Plasmodium knowlesi
-
 CMP + phosphatidyl-1D-myo-inositol
-
 r

Organism

Organism UniProt Comment Textmining
Plasmodium knowlesi
-
 erythrocytes infected with
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
CDP-diacylglycerol + myo-inositol
-
 Plasmodium knowlesi CMP + phosphatidyl-1D-myo-inositol
-
 r

Subunits

Subunits Comment Organism
monomer SDS-PAGE Plasmodium knowlesi

Synonyms

Synonyms Comment Organism
cytidine 5'-diphospho-1,2-diacyl-sn-glycerol: myoinositol 3-phosphatidyl transferase
-
 Plasmodium knowlesi
PI synthase
-
 Plasmodium knowlesi

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Plasmodium knowlesi